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Τι (ποιος) είναι G protein-coupled receptor - ορισμός
G protein-coupled receptor
![PDB]] entry [https://web.archive.org/web/20180128134132/https://www.rcsb.org/structure/3SN6 3SN6]). The receptor is colored red, Gα green, Gβ cyan, and Gγ yellow. The C-terminus of Gα is located in a cavity created by an outward movement of the cytoplasmic parts of TM5 and 6.](https://commons.wikimedia.org/wiki/Special:FilePath/Beta2Receptor-with-Gs.png?width=200 "PDB]] entry [https://web.archive.org/web/20180128134132/https://www.rcsb.org/structure/3SN6 3SN6]). The receptor is colored red, Gα green, Gβ cyan, and Gγ yellow. The C-terminus of Gα is located in a cavity created by an outward movement of the cytoplasmic parts of TM5 and 6.")
![Proposed downstream interactions between [[integrin]] signaling and GPCRs. Integrins are shown elevating Ca<sup>2+</sup> and phosphorylating FAK, which is weakening GPCR signaling.](https://commons.wikimedia.org/wiki/Special:FilePath/GPCR and itegrin signaling diagram.png?width=200 "Proposed downstream interactions between [[integrin]] signaling and GPCRs. Integrins are shown elevating Ca<sup>2+</sup> and phosphorylating FAK, which is weakening GPCR signaling.")
LARGE PROTEIN FAMILY OF RECEPTORS THAT DETECT MOLECULES OUTSIDE THE CELL AND ACTIVATE INTERNAL SIGNAL TRANSDUCTION PATHWAYS AND CELLULAR RESPONSES
G-protein coupled receptors; G-protein coupled receptor; 7TM receptor; G protein coupled receptor; GPCR; Heptahelical receptor; 7 transmembrane receptor; Seven transmembrane receptor; Seven-transmembrane protein; Seven transmembrane region; G-protein-coupled receptors; Guanine Nucleotide-Binding Protein-Coupled Receptor; 7TM Receptor; 7TM; G-protein-coupled receptor; Receptors, g-protein-coupled; 7-transmembrane G-protein coupled; G-protein coupled; G protein-coupled; 7 transmembrane; 7-transmembrane; G-protein linked receptors; G-protein coupled membrane receptors; G protein-coupled receptors; G-protein-coupled; Serpentine receptor; G protein coupled receptors; Gi coupled receptor; Seven transmembrane protein; 7-transmembrane receptor; Gpcr; Gpcrs; G protein–coupled receptor; GPCRs
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily-related proteins that are cell surface receptors that detect molecules outside the cell and activate cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times.
Adhesion G protein-coupled receptor
CLASS OF 33 HUMAN PROTEIN RECEPTORS
User:Martstacey/sandbox; Adhesion gpcr; Adhesion-GPCR; Adhesion gpcrs; Adhesion-GPCRs; Adhesion G protein-coupled receptors
Adhesion G protein-coupled receptors (adhesion GPCRs) are a class of 33 human protein receptors with a broad distribution in embryonic and larval cells, cells of the reproductive tract, neurons, leukocytes, and a variety of tumours. Adhesion GPCRs are found throughout metazoans and are also found in single-celled colony forming choanoflagellates such as Monosiga brevicollis and unicellular organisms such as Filasterea.
Retinoic acid-inducible orphan G protein-coupled receptor
GROUP OF G PROTEIN-COUPLED RECEPTORS
Retinoic acid-inducible orphan G-protein-coupled receptor; RAIG; GPRC5 receptor
The Retinoic Acid-Inducible orphan G-protein-coupled receptors (RAIG) are a group of four closely related G protein-coupled receptors whose expression is induced by retinoic acid.
